Thioredoxin相关论文
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Magnaporthe oryzae, the causal agent of rice blast disease, is one of the most devasting threats to food security worldw......
Thioredoxin-1 Plays Important Role in Estrogen-meidated Cardiomyocyte Protection in Hydrogen Peroxid
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Type-2 diabetes is a metabolic disease.This study has revealed that the activity of serum thioredoxin(Trx)appears as a g......
The mechanism and key molecules of diabetic retinopathy are unknown.Effects of different light intensities on retinal ph......
目的:T细胞受体(TCR)选择是T细胞发育过程中非常重要的事件;完成了TCR重排的双阳性T细胞(DP)经历阳性选择后发育为CD4+或CD8+T细胞,这......
会议
Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibro
Objective This study aimed to investigate the possible mechanism that silica interfered thioredoxin (Trx) system during ......
Levels of thioredoxin are related to the severity of obstructive sleep apnea: based on oxidative str
Background Oxidative stress is a typical feature of obstructive sleep apnea (OSA).Thioredoxin (TRX), as one of the oxida......
Protective effect and mechanism of thioredoxin on Neuro2a cell apoptosis induced by advanced glycati
Advanced glycation end-products affect most of types of cells and molecules in the human body.Specifically, several stud......
Cloning, Expression, and Bioinformatic Characterization of a Novel Marine Emiliania huxleyi Viral(Co
Thioredoxin (Trx) is a small ubiquitous protein that displays different functions mainly via redox-mediated processes.We......
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Reduced toxicity of irinotecan by combining selenium nanoparticle while improving the therapeutic ef
Although chemotherapeutic drugs are widely applied for clinic tumor treatment,severe toxicity restricts their therapeuti......
Thioredoxin(Trx)is an important reducing enzyme and is usually overexpressed in tumor cells.Photoactive platinum(Ⅳ)anti......
Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibro
Silicosis is one of the most prevalent occupational lung diseases worldwide.This study aimed to investigate the poss......
根据GenBank中肉鸡硫氧还蛋白(Trx)基因的cDNA序列及载体pET28a(+)中的多克隆位点设计引物,进行Trx克隆和原核表达载体的构建,并在......
氧化还原蛋白“硫氧还蛋白”和脂肪细胞因子“脂联素”间的关系鲜有报道.我们发现,慢性阻塞性肺疾病急性发作期(AECOPD)患者,随着......
本研究旨在观察2型糖尿病大鼠心肌损伤时硫氧还蛋白(thioredoxin,Trx)系统在心肌组织中的活性变化,并探讨其机制。成年Sprague Daw......
目的:探讨血清和腹水中硫氧还蛋白(thioredoxin,TRX)及硫氧还蛋白结合蛋白-2(Trxbinding protein-2,TBP-2)的含量与子宫内膜异位症......
Selenium(Se)was discovered by Swedish chemist Jacob Berzelius(1779-1848)on 1817 and has become one of the most influenti......
Serum thioredoxin activity:a promising biomarker for assessment of coronary stenosis severity in pat
Coronary artery disease(CAD)is one of the major death causes worldwide.Therapeutic methods may improve the progress of C......
A transgenic barley line(LSY-11-1-1) with overexpressed Phalaris coerulescens thioredoxin gene(PTrx) was employed to mea......
硫氧还蛋白(Trx)系统是体内重要的巯基氧化还原系统,能够阻止炎症反应的发生,并维持细胞氧化还原的动态平衡.硫氧还蛋白系统主要由......
硫氧还蛋白(TRx)是一种广泛表达于真核细胞和原核细胞的内源性蛋白质,其活性位点的邻位双巯基使其具有强大的还原活性,能有效还原......
目的 观察重组人硫氧还蛋白(TRX)对柯萨奇B3m病毒(CVB3m)致HeLa细胞损伤的保护作用,并检测TRX对病毒复制的抑制作用.方法 采用IOTC......
硫氧还蛋白(thioredoxin,TRX)是硫氧还蛋白系统中最重要的物质,后者还包括硫氧还蛋白还原酶(thioredoxin reductase,TRXR)和还原型辅酶Ⅱ(N......
目的观察亚砷酸钠(NaAsO2)对大鼠肝脏硫氧还蛋白(TRX)系统相关基因mRNA表达的影响。方法选用Wistar大鼠36只,雌雄各半,按体质量采用随机......
目的 探讨硫氧还蛋白对大鼠睾丸缺血再灌注损伤的保护作用.方法 选取雄性SD大鼠60只,随机分为4组:假手术对照组(A组);睾丸扭转/复......
目的:初步探讨β淀粉样蛋白1~42(Aβ1~42)及D-半乳糖(D-gal)联合构建的复合型阿尔茨海默病(AD)模型,以及模型中硫氧还蛋白与凋亡相关蛋白的研......
目的探讨脂多糖(LPS)诱导大鼠肝细胞内质网应激(ERS)过程中硫氧还蛋白-1(Trx-1)的变化及其作用机制。方法①体外培养大鼠肝细胞株BRL,取部......
目的观察急性肾盂肾炎(APN)患儿血清硫氧还原蛋白(S-Trx)、尿Trx(U-Trx)水平以及血清和尿液Trx比值(S-Trx/U-Trx),探讨其在APN早期诊断和病......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 观察重组人硫氧还蛋白(TRX)对病毒性心肌炎小鼠心肌损伤的保护作用.方法 给予Balb/c小鼠腹腔注射0.1 ml 100TCID50(50%细胞感......
Proteomic analysis reveals molecular biological details in varioliform gastritis without Helicobacte
AIM:To investigate and elucidate the molecular mechanism underlying varioliform gastritis for early detection,prevention......
Recombinant adeno-associated virus delivered human thioredoxin-PR39 prevents hypoxia-induced apoptos
Human thioredoxin and antibacterial peptide, PR39, have been shown to have potent antioxidant effects that may prolong s......
Downregulation of thioredoxin reductase 1 expression in the substantia nigra pars compacta of Parkin
Because neurons are susceptible to oxidative damage and thioredoxin reductase 1 is extensively distributed in the centra......
A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative
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S-adenosyl-L-methionine modifies antioxidant-enzymes, glutathione-biosynthesis and methionine adenos
AIM: To elucidate the mechanism(s) by which S-adenosyl-L-methionine(SAM) decreases hepatitis C virus(HCV) expression.MET......
Mutagenesis of the conserved Gly and Pro residues between the catalytic half-cystines in human thior
A plasmid pACA/Trx was constructed containing the human thioredoxingene under T7 promoter control. To examine the role o......
AIM To study the sensitivity and antioxidant enzyme response in two clinical isolates of Entamoeba histolytica(E. histol......
Translation factor SelB is the key component for the specific decoding of UGA codons with selenocysteine at the ribosome......
There is very convincing evidence that a high dietary level of selenium substantially reduces the incidence of a wide va......
Thioredoxin (Trx) is a small ubiquitous dithiol protein which together with the FADcontaining enzyme thioredoxin reducta......
抗氧化剂酶在保护线虫和吸虫兔受反应性氧族ROS损伤中具有重要作用,也有些虫种虽缺乏代谢过氧化氢的触酶及谷胱甘肽过氧化物酶(GP......
Thioredoxin is a ubiquitous dithiol oxidoreductase found in many organisms and involved in numerous biochemical process......
Objective: To obtain recombinant human SDF-1β expressed in E. coli and purify SDF-lfi with bio-logical activity from th......
目的:克隆人白细胞硫氧还蛋白还原酶(thioredoxin reductase,TR)编码区的cDNA并进行序列分析。方法:采用RT-PCR方法获得TR基因cDNA......
High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-ret
AIM To elucidate how high diet-induced endoplasmic reticulum-stress upregulates thioredoxin interacting protein expressi......